Psoriatic Arthritis is a type of chronic inflammatory arthritis that primarily affects toes and fingers followed by nail or skin psoriasis. The clinical features are varied but the major symptoms are peripheral arthritis, enthesitis, psoriasis, dactylitis and axial disease. According to Arthritis Foundation, the prevalence of psoriatic arthritis in patients suffering from psoriasis is approximately between 7% and 48%. Psoriatic arthritis appears most often between the age of 30 years and 50 years. The factors contributing to the pathogenesis of psoriatic arthritis are genetic factors, environmental factors and immunological factors. Genetic factors explain that 40% of the psoriatic arthritis has family history of skin and joint diseases. Environmental factors such as bacterial and viral infections have been implicated as a cause in psoriatic arthritis. Immunological factors consist of cytokines such as TNF-α which is critically involved in inflammatory process, leading to bone and cartilage degradation as well as skin inflammation. There are five different types of psoriatic arthritis that includes different joints and spinal column. There are two types of method by which psoriatic arthritis is diagnosed by imaging and laboratory test. Imaging tests consist of X-Rays and magnetic resonance imaging and laboratories consists of rheumatoid factor and joint fluid test.

Browse Full Report with TOC @ http://www.transparencymarketresearch.com/psoriatic-arthritis-pharmacotherapy.html

The pharmacotherapy of psoriatic arthritis consists of drugs such as DMARDs (disease modifying anti-rheumatic drugs), NSAIDs, Immunosuppressant and TNF-α inhibitors. In chronic conditions surgeries and other procedures are practiced such as steroid injections and joint replacement surgery. The DMARDs consists of drug that reduces the progression of psoriatic arthritis and protect joints and other tissues from irreversible damage, it includes drugs such as methotrexate, sulfasalazine and leflunomide. The NSAIDs help to relive the pain and reduction of inflammation and most of them are OTC drugs including Ibuprofen and naproxen sodium. While immunosuppressant helps to control the immune system including azathioprine and cyclosporine. TNF-α inhibitors assist reducing pain, swollen joints and morning stiffness this class of drug includes etanercept, infliximab, adalimumab, Humira, certolizumab and golimumab.

Some of the major factors driving the psoriatic arthritis market are rising geriatric population, increasing incidences of psoriatic arthritis and major onset for growth in this market is expected from the launch of blockbuster drugs such as Simponi and Vicodin along with many impending biologics that are in late stage of development. The major factors restraining the growth of psoriatic arthritis pharmacotherapy market are the new biologics that are observed to be highly efficient but come with high cost. Lack of patient awareness is one of the major factor affecting the growth of psoriatic arthritis pharmacotherapy market according to CDC (Center of Disease Control and Prevention) nearly 10% – 12% of the patients visit clinics during the chronic stage of psoriatic arthritis as most of them ignore initial symptoms which are very common like skin reddening along with a joint pain or a skin rash.

North America was observed to be the leading geography due to high prevalence of psoriatic arthritis followed by availability of modern healthcare facilities is assisting the growth of this market. Europe is the second largest market for psoriatic arthritis pharmacotherapy as it’s the region expected to observe rapid aging population. Asia-Pacific and Rest of the World are the most attractive and growing markets in psoriatic arthritis pharmacotherapy. In Asia-Pacific China, India, Japan, South Korea and Australia are observed to be the leading geographies in psoriatic arthritis.

The psoriatic arthritis pharmacotherapy market is predominantly led by the players such as Pfizer, Inc., Amgen, Inc., Merck & Co, Inc., F. Hoffmann-La Roche Ltd, Johnson & Johnson, Abbott Laboratories and Novartis International AG. It was observed that Abbott Laboratories, Johnson and Johnson and Amgen, Inc. account for the major market share in psoriatic arthritis pharmacotherapy.

This research report analyzes this market on the basis of its market segments, major geographies, and current market trends. Geographies analyzed under this research report include

  • North America
  • Asia Pacific
  • Europe
  • Middle East and Africa
  • Latin America

This report provides comprehensive analysis of

  • Market growth drivers
  • Factors limiting market growth
  • Current market trends
  • Market structure
  • Market projections for upcoming years

This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.

Read More Reports on Pharmaceutical Market: http://www.transparencymarketresearch.com/pharmaceutical-market-reports-1.html

About us

Transparency Market Research (TMR) is a market intelligence company providing global business research reports and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision-makers.

TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. Our business offerings represent the latest and the most reliable information which is indispensable for businesses to sustain their competitive edge.

Inquiry Before Buying: http://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=1065

Latest Press Release Reports: http://www.transparencymarketresearch.com/press-releases.htm

Latest Articles Reports: http://www.transparencymarketresearch.com/articles.htm

Contact Us

Mr. Nachiket Ghumare
Corporate Office:
State Tower,
90 State Street,
Suite 700,
Albany NY – 12207
United States.

Tel: +1-518-618-1030
Email: sales@transparencymarketresearch.com
Website: http://www.transparencymarketresearch.com

Browse market research blog:
https://pharmaceuticalmarket.wordpress.com/

Technology_Media
A portable charger used to charge a wide range of digital product is called power bank. Power bank is also called battery charger. It is used as back-up charger, an external battery or plug-in charger for charging battery cells or rechargeable battery. Power bank is a suitable way to charge electronic device whenever and wherever needed. Mobile devices, digital cameras, laptops and tablets can be charged using power bank. The power bank is designed on the basis of device being charged. Power bank can be re-used and recharged. Milliampere-hour is the measuring unit for the capacity of power bank. Higher Milliampere results in the higher storing capacity of power banks. Power bank comprise of lithium batteries as they are affordable, compact in nature and widely available. A power bank is different from each other even though the battery capacity is exactly the same; in terms of compatibility, pricing, cell quality, internal design, size and cell grade. Power bank batteries are categorized as cylindrical battery, square aluminum case and polymer battery. Due to the high mechanized cost for battery cell made of Lithium-Polymer comparing it to Lithium-Ion, the price of power bank made of Lithium-Polymer battery is higher than the power bank comprise with Lithium-Ion battery. Casing made from standard shell offer protection from any leakage or harm from the power bank. A power bank in general will require 5V/1A for optimum charging period across the globe. Power bank quality, cell PCB board design, actual capacity and reliability are factors determining approximately device charge per cycle.Browse Full Report with TOC:
http://www.transparencymarketresearch.com/power-banks-market.html

Mobility and versatility are the most important features of power bank. Power bank are available in various sizes, shapes, capacities and colors. Global power bank market can be segmented on the basis of application and product type. Mobile phone chargers and Electric vehicle chargers are segments of applications. Solar power bank, power bank with LED and built-in rechargeable line are segments of power bank products.

Improved living standards, increased consumer purchasing power and rising economies are uplifting electronics market. The demand for power bank rises as electronic devices comes with low battery capacity. Longer duration usage of smart phone, increased demand of smart phone and increased usage of tablets has spurred the market growth of power bank globally. Functionality of electronic devices are increasing, propelling power bank market. Smart phone battery life has been a problem for consumer. This constraint has become opportunity for power bank companies. Safety is a concern as low grade power cells can be volatile based if overcharged in case of lithium-ion battery.

China is the important player in the power bank market, increasing demand across the world is increasing opportunities globally. Cell phones are sweeping the developing world as the technology become cheap. Growth of power bank market will increasingly rely on emerging market as Western Europe, Japan and North America reach saturation. Power bank is expected to attain success in developing nation where the power grid is lacking.

Some of the global players in power bank market are BYD Battery Company Limited, Energizer Holding INC, LG Chem Power Inc., Philips, Sony Corporation, Lishen, Buffalo Technology, Samsung Electronics, Ultralife Corporation and Sanyo among others. Research & developments and innovations are adopted by the companies as the strategies to rise in the power bank market.

This research report analyzes this market on the basis of its market segments, major geographies, and current market trends. Geographies analyzed under this research report include

North America
Asia Pacific
Europe
Rest of the World

This report provides comprehensive analysis of

Market growth drivers
Factors limiting market growth
Current market trends
Market structure
Market projections for upcoming years

This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.

Read More Reports on Technology & Media Market:
http://www.transparencymarketresearch.com/technology-market-reports-8.html

About us

Transparency Market Research (TMR) is a market intelligence company providing global business research reports and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision-makers.

TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. Our business offerings represent the latest and the most reliable information which is indispensable for businesses to sustain their competitive edge.

Inquiry Before Buying @ http://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=4105

Latest Press Release Reports: http://www.transparencymarketresearch.com/press-releases.htm

Latest Articles Reports: http://www.transparencymarketresearch.com/articles.htm

Contact Us

Mr. Atil Chaudhari
Corporate Office:
State Tower,
90 State Street,
Suite 700,
Albany NY – 12207
United States.

Tel: +1-518-618-1030
Email: sales@transparencymarketresearch.com
Website: http://www.transparencymarketresearch.com

Browse market research blog:
http://tmrmarkets.blogspot.co.uk/

According to a new market report published by Transparency Market Research “Urodynamics Equipment and Disposables Market – Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 – 2020”, the global urodynamics equipment and disposables market was valued at USD 140.4 million in 2013 and is expected to grow at a CAGR of 6.1% during the forecast period from 2014 to 2020 to reach USD 216.3 million in 2020.

We are currently offering a flat 15% discount on all purchases until end of the March 2015!
http://www.transparencymarketresearch.com/urodynamics-equipment-disposables-market.html

Urodynamics tests comprise a range of examinations that are useful for obtaining functional information regarding bladder filling, emptying and urine storage. The focal objective of urodynamics is to comprehend the dysfunction of lower urinary tract by replicating the patient’s symptoms, when present, and determining the cause of these symptoms by suitable urodynamics investigations that would help in programming an appropriate treatment regimen for bladder dysfunction (e.g. urinary incontinence, stress incontinence, bladder neck obstruction, prostatitis, and benign prostatic hyperplasia, etc.).

Uroflowmetry equipment, cystometer, ambulatory urodynamic systems, electromyographs and video urodynamic systems cumulatively form the urodynamics equipment market; among which uroflowmetry equipment emerged as the segment leader in terms of revenue (generating over USD 30 million) in 2013. This has been attributed to the easy availability, high patient and physician preference. On the other hand, ambulatory urodynamics systems are expected to exhibit the highest growth rate of over 8.5% during the forecast period 2014 to 2020 due to their widespread market availability, portable design and advanced microprocessor technology that help these devices in delivering reliable test outcomes.

Furthermore, within the disposables segment, air-charged catheters accounted for the largest market share of the total urodynamics disposables market in 2013. Air-charged catheters are expected to lead the market during the forecast period from 2014 to 2020, at the highest CAGR of 6.7%. Benefits of air-charged catheters such as ease of handling, absence of air-bubble interference coupled with presence of weightless air column are some of the major driving factors of these catheters in the urodynamics disposables market.

Download Free PDF: Urodynamics Equipment and Disposables Market – Global Industry Trends and Forecast 2014 – 2020

In terms of regional distribution, North America dominated the global urodynamics equipment and disposables market in 2013 and accounted for a share of over 40% of the global market in the same year. High adoption rate of urodynamics tests among urologists and urogynecologists along with presence of large number of testing centers across the region are some of the major factors that are boosting the growth of this market in North America. Moreover, growing incidence of urological dysfunctions and perpetual innovations in the nature of urodynamics capital equipment are some of the additional factors that are driving the growth of this market. Asia Pacific, on the other hand, witnessed the highest growth rate in the urodynamics equipment and disposables market. The ever-growing, price-sensitive population in the developing countries of Asia coupled with growth in incidence of urological dysfunctions among the geriatric population is expected to boost the urodynamics equipment and disposables market in the region during the forecast period.

The urodynamics equipment and disposables market is highly fragmented due to the large presence of equipment manufacturers and providers that generally range from local to global enterprises. The global urodynamics equipment and disposables market, therefore, is characterized by the presence of only a few renowned market players. These include Albyn Medical S.L., American Medical Systems, Inc., CooperSurgical, Inc., Covidien plc, C. R. Bard, Inc., HealthTronics, Inc., LABORIE, Medical Measurement Systems B.V. and Verathon, Inc. Among these, in 2013, LABORIE held the largest market share of the total global urodynamics equipment and disposables market at over 50%. Its market leadership was attributed to several factors such as strong distribution channels, extensive product portfolio and well managed supply competence. The market is expected to remain highly competitive in the next few years with the entry of other global players in the urodynamics equipment and disposables market.

See More Articles: https://www.linkedin.com/today/author/263590413

The global urodynamics equipment and disposables market is segmented as follows:

Global Urodynamics Equipment and Disposables Market, by Type of Products

  • Uroflowmetry Equipment
  • Cystometers
  • Ambulatory Urodynamics Systems
  • Electromyographs
  • Video Urodynamics Systems
  • Urodynamics Disposables
  1. Air-charged Catheters
  2. Water-filled Catheters
  3. Infusion, Extension & Perfusion Pump Tubing Sets
  4. Transducer Sets

Global Urodynamics Equipment and Disposables Market, by Geography

  • North America
  • Europe
  • Asia Pacific
  • Rest of the World (RoW)

Read More Reports on Medical Devices Market: http://www.transparencymarketresearch.com/medical-devices-market-reports-6.html

About us

Transparency Market Research (TMR) is a market intelligence company providing global business research reports and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision-makers.

TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. Our business offerings represent the latest and the most reliable information which is indispensable for businesses to sustain their competitive edge.

Inquiry Before Buying @ http://www.transparencymarketresearch.com/sample/sample.php?flag=S&rep_id=2255

Latest Press Release Reports: http://www.transparencymarketresearch.com/press-releases.htm

Latest Articles Reports: http://www.transparencymarketresearch.com/articles.htm

Contact Us

Mr. Nachiket Ghumare
Corporate Office:
State Tower,
90 State Street,
Suite 700,
Albany NY – 12207
United States.

Tel: +1-518-618-1030
Email: sales@transparencymarketresearch.com
Website: http://www.transparencymarketresearch.com

Browse market research blog:
http://tmrmarkets.blogspot.co.uk/
https://medicaldeviceresearch.wordpress.com/

Apoptosis is the death of cell in a programmed fashion that is observed largely in multicellular organisms. This programmed cell death occurs in a cascade of biochemical events which include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation and chromosomal fragmentation. Anywhere between 50 and 70 billion cells die each day due to apoptosis in the average human adult. This cascade has been hypothesized to be exploited as an ideal method of anti-cancer strategy traditionally by inducing DNA damage with chemotherapy and radiotherapy.

Browse the full Apoptotic Therapeutics In Oncology Market Repoprt with TOC @ http://www.transparencymarketresearch.com/apoptotic-therapeutics-oncology-market.html

These methods have been the backbone of most anti-cancer therapies today, but with increasing knowledge of intrinsic and extrinsic pathways of apoptosis, innovative apoptotic agents have been under investigation since the past several years. There are currently several of these agents in clinical trials for potential role in cancer therapeutics and are expected to become another weapon in our arsenal for the fight against cancer. In technical process death receptors CD95, death receptor DR4 and DR5 along with tumor necrosis factor receptor 1 TNFR1 can effectively induce apoptosis when bound by their ligands. Significant evidence obtained in several animal models confirms the validity of strategies for targeted apoptosis and has revealed an enormous potential for therapeutic intervention in a variety of illnesses. Almost all key participant proteins in cellular apoptosis regulation have been identified and can be targeted by therapeutic strategies which include above mentioned death receptors, Bcl-2 proteins, caspases, endogenous caspase inhibitors and transcriptional regulators.

The current scenario is quite challenging with greater restraints than drivers due to low success ratio. The superior tumor killing activity of TRAIL agonists and the toxic side effects associated with systemic treatment of other death ligands. In animal models a great degree of success was achieved for treatment against inflammatory bowel disease with the help of anti-TNF antibodies or genetic TNF knockout. WHO predicted that annual cancer cases will reach to 19.3 million by 2025 from the 14.1 million annually in year 2012. There were 8.2 million deaths from cancer in the world in 2012 according to cancer research U.K. More than 60% of world’s total new annual cases occur in Africa, Asia and Central and South America. These regions account for 70% of the world’s cancer deaths. This also represents a sizable opportunity for innovative cancer therapeutics companies worldwide. Current economic scenario indicates an improving purchase power and increasing investment in healthcare in developing countries which also governs the fact that emerging players in this arena can profit considerably contrary to conventional observations that profit can be gained only from developed regions such as North America and Europe.

Current companies that are involved in the research and development of targeted apoptosis therapeutics include Genentech and Amgen are in the process of conducting phase-1 clinical trials for soluble TRAIL agonists as anti-cancer agents. An agonistic TRAIL-R2 antibody (TRA-8) was generated by Sankyo Co., Ltd. (Tokyo, Japan) and proved to be cytotoxic against primary hepatocellular carcinoma cells without inducing cell death in normal hepatocytes. Human Genome Sciences Inc. has recently enrolled patients in phase 2 clinical trials with the TRAIL-R1-specific human monoclonal antibody HGS-ETR1 for the treatment of nonsmall cell lung cancer, colorectal carcinoma, and non-Hodgkin lymphoma. According to the study, approximately six of 57 patients enrolled even reached a stable disease situation. GlaxoSmithKline disclosed a series of similar piperidinyl substituted isatins and related 5-alkylaminosulphonyl-3,3-dichloro-oxindoles. With this, Pfizer has also continued research in caspase inhibitors such as isatin-based caspase inhibitors, from which the compound MMPSI, a (2-methoxymethylpyrrolidinyl)-sulfonylisatin, was able to reduce ischemic injury. This can also be used in targeted apoptosis for cancers. Several Merck inhibitors are currently in preclinical trials.

This research report analyzes this market on the basis of its market segments, major geographies, and current market trends. Geographies analyzed under this research report include

  • North America
  • Asia Pacific
  • Europe
  • Rest of the World

This report provides comprehensive analysis of

  • Market growth drivers
  • Factors limiting market growth
  • Current market trends
  • Market structure
  • Market projections for upcoming years

This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.

Read More Reports on Pharmaceutical Market: http://www.transparencymarketresearch.com/pharmaceutical-market-reports-1.html

About us

Transparency Market Research (TMR) is a market intelligence company providing global business research reports and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision-makers.

TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources along with various tools and techniques to gather and analyze information. Our business offerings represent the latest and the most reliable information which is indispensable for businesses to sustain their competitive edge.

Inquiry Before Buying @ http://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=3574

Latest Upcoming Reports: http://www.transparencymarketresearch.com/upcoming.htm

Follow In Linked In: https://www.linkedin.com/pulse/article/20141106060355-263590413-apoptotic-therapeutics-in-oncology-market

Contact Us

Sheela AK
Corporate Office:
State Tower,
90 State Street,
Suite 700,
Albany NY – 12207
United States.

Tel: +1-518-618-1030
Email: sales@transparencymarketresearch.com
Website: http://www.transparencymarketresearch.com

Browse market research blog:
http://www.tmrblog.com/

The global smart watches market is expected to show a remarkable growth rate by coming years. One of the major factors contributing the growth of the global smart watches market is the entrance of big vendors in the market. The market has also witnessing an increase in R&D spending. The global leading players such as Sony, Samsung, Pebble, and Maritime have increased their R&D investments for smart watches. For that, they are entering into partnerships with value-added resellers and suppliers and investing in R&D activities. These increasing R&D investments are helping players to introduce new products with better integration ability and accuracy. This will help with the reduction in smart watch prices and lead to an increase in their adoption among consumers.

Source @ Global Smart Watches Market Segment Forecasts up to 2020.